Vascular Endothelial Growth Factor (VEGF) Trap Studies from Regeneron:

VIEW 1 is a study of the efficacy and safety of intravitreal VEGF Trap in patients with neovascular age-related macular degeneration (AMD).

DA VINCI is a study of the efficacy and safety of intravitreal VEGF Trap in patients with diabetic macular edema (DME) compared to focal laser treatment.

Lucentis (Ranibizumab) Studies from Genentech:

BRAVO is a study of the efficacy and safety of intravitreal Lucentis compared with sham injections in patients with macular edema secondary to branch retinal vein occlusion (BRVO).

CRUISE is a study of the efficacy and safety of intravitreal Lucentis compared with sham injections in patients with macular edema secondary to central retinal vein occlusion (CRVO).

RIDE is a study of the efficacy and safety of intravitreal Lucentis in patients with clinically significant macular edema with center involvement (CSME-CI) secondary to diabetes mellitus (Type 1 or 2).

HARBOR is a study comparing high dose intravitreal Lucentis with standard dose Lucentis for the treatment of neovascular AMD.

Sirolimus (Rapamycin) Studies from MacuSight:

DIAMOND is a dose ranging study of subconjunctival sirolimus in patients with diabetic macular edema.

EMERALD is a dose ranging study of subconjunctival sirolimus with Lucentis versus Lucentis alone for the treatment of neovascular AMD.

Fluocinolone Implant Study From Alimera:

FAME is a study evaluating the safety and efficacy of an intravitreal steroid insert of fluocinolone acetonide for the treatment of diabetic macular edema.

Ocular Melanoma Study:

CSTIP is a study using combined simultaneous photodynamic therapy and transpupillary thermotherapy with indocyanine green to treat small and medium-sized choroidal melanomas. This is combined with the use of intravitreal ranibizumab (Lucentis) in order to allow for fewer treatments.

To learn more visit www.clinicaltrials.gov