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Vascular Endothelial Growth Factor (VEGF) Trap Studies from Regeneron:
VIEW 1 is a study of the efficacy and safety of intravitreal VEGF Trap in patients with neovascular age-related macular degeneration (AMD).
DA VINCI is a study of the efficacy and safety of intravitreal VEGF Trap in patients with diabetic macular edema (DME) compared to focal laser treatment.
Lucentis (Ranibizumab) Studies from Genentech:
BRAVO is a study of the efficacy and safety of intravitreal Lucentis compared with sham injections in patients with macular edema secondary to branch retinal vein occlusion (BRVO).
CRUISE is a study of the efficacy and safety of intravitreal Lucentis compared with sham injections in patients with macular edema secondary to central retinal vein occlusion (CRVO).
RIDE is a study of the efficacy and safety of intravitreal Lucentis in patients with clinically significant macular edema with center involvement (CSME-CI) secondary to diabetes mellitus (Type 1 or 2).
HARBOR is a study comparing high dose intravitreal Lucentis with standard dose Lucentis for the treatment of neovascular AMD.
Sirolimus (Rapamycin) Studies from MacuSight:
DIAMOND is a dose ranging study of subconjunctival sirolimus in patients with diabetic macular edema.
EMERALD is a dose ranging study of subconjunctival sirolimus with Lucentis versus Lucentis alone for the treatment of neovascular AMD.
Fluocinolone Implant Study From Alimera:
FAME is a study evaluating the safety and efficacy of an intravitreal steroid insert of fluocinolone acetonide for the treatment of diabetic macular edema.
Ocular Melanoma Study:
CSTIP is a study using combined simultaneous photodynamic therapy and transpupillary thermotherapy with indocyanine green to treat small and medium-sized choroidal melanomas. This is combined with the use of intravitreal ranibizumab (Lucentis) in order to allow for fewer treatments.
To learn more visit www.clinicaltrials.gov |